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7/14/09

EAT LESS LIVE MORE YET MORE STUDIES AND REPORTS ABOUT LOW CALORIE DIETS AND LIVING LONGER AS WELL AS MORE DRUGS THAT MAY WORK LIKE RESVERATROL

EAT LESS LIVE MORE YET MORE STUDIES AND REPORTS ABOUT LOW CALORIE DIETS AND LIVING LONGER AS WELL AS MORE DRUGS THAT MAY WORK LIKE RESVERATROL

I have written before about the observation that some animals that are on a low calorie diet seem to live longer. Two more reports about ways to live longer were released recently. One report asked do monkeys who eat less live longer? The second report talked about the drug rapamycin, which seemed to prolong life in mice, described as an antibiotic and immunosuppresant I am more familiar with it as a coating for stents that are placed in clogged heart arteries. Could rapamycin be acting in an analogous fashion to resveratrol?





  • Dieting Monkeys Offer Hope of Living Longer
  • Rapamycin extends life in mice, raising hopes of life-prolonging drug for humans
  • Hamburgers in Orbit NYT Shoots Down Copacetic Image of Hamburger

    Can Eating Less Food and Consuming Fewer Calories Help People Live Longer?..Research Suggests Inverse Correlation Between Number of Calories and Length of Life..





    Should Ponce De Leon Just Have Gone on A Diet? Key to Longevity: Not Fountain of Youth But Fork of Youth? The Calerie Study Searches for The Key



    An expanding volume of scientific research seems to imply that eating fewer calories and eating less is associated with living longer. It has been reported for many years that chronic calorie restriction without nutritional defiencies increases the length of life. Calorie restriction seems to help prevent some age-related chronic diseases such as cancer, diabetes, and cardiovascular disease in a variety of animals.Is this true in humans?
  • Science Friday:Audio of Dr. Eric Ravussin on Benefits of Calorie Restriction
  • Effect of 6-Month Calorie Restriction on Biomarkers of Longevity, Metabolic Adaptation, and Oxidative Stress in Overweight Individuals
  • Calorie Restriction Extends Life Span— But Which Calories?
  • Three Physiological Measures Linked To Longevity in Men and
  • Eat Less, Live Longer? The Quest to Learn Why Slashing Calories Extends Life and
  • Aging: A Biological Perspective



    CALERIE Eat Less Live More

    CALERIE Comprehensive Assessment of Long-term Effects of Reducing Intake of Energy is an ongoing study with human volunteers that hopes to discover whether people who eat less live longer.

    Calorie Restriction for Long Life Paradigm Known for 6o Years

    To quote from an article Caloric Restriction in Primates "Dietary caloric restriction (CR) is the only intervention conclusively and reproducibly shown to slow aging and maintain health and vitality in mammals. Although this paradigm has been known for over 60 years, its precise biological mechanisms and applicability to humans remain unknown. We began addressing the latter question in 1987 with the first controlled study of CR in primates (rhesus and squirrel monkeys, which are evolutionarily much closer to humans than the rodents most frequently employed in CR studies). To date, our results strongly suggest that the same beneficial "antiaging" and/or "antidisease" effects observed in CR rodents also occur in primates. These include lower plasma insulin levels and greater sensitivity; lower body temperatures; reduced cholesterol, triglycerides, blood pressure, and arterial stiffness; elevated HDL; and slower age-related decline in circulating levels of DHEAS. Collectively, these biomarkers suggest that CR primates will be less likely to incur diabetes, cardiovascular problems, and other age-related diseases and may in fact be aging more slowly than fully fed counterparts. Despite these very encouraging results, it is unlikely that most humans would be willing to maintain a 30% reduced diet for the bulk of their adult life span, even if it meant more healthy years. "



    What is it about Eating Fewer Calories That Increases Longevity also the New England Centenarian Study



    So scientists have been trying to determine what if anything is happening in caloric restriction that would prolong life. See
  • Molecules Discovered that Extend Life in Yeast, Human Cells and
  • Eating Less and Living Longer: Can’t We Find an Easier Way?
  • plus Gene That Extends Lifespan In Yeast Points To Paradigm Shift In Longevity Research May Explain Life Extension Via Calorie Restriction

    Look at
  • Study: Lean Diet May Mean Long Life and also
  • Eat Less Live Longer as well as
  • Meal Skipping Helps Rodents Resist Diabetes, Brain Damage and also see Fasting Forestalls Huntington’s Disease in Mice and also
  • Protein Structure Provides Clue to Long Life

    New England Centenarian Study

    On a related note examine the New England Centenarian Study at Boston University School of Medicine that tries to figure out factors that help people to live longer.